Fulminant hemophagocytic lymphohistiocytosis secondary to a reactivated EBV infection: A case report. Corticosteroid-resistant non-responders may benefit from second-line therapies, such as CyA 2. More recently biologic agents directed against inflammatory cytokines IL-1 and IL-6 have been shown to be helpful in some patients. Blood ; 19 : —
Ala91Val reported in Case 1 has been extensively studied and remains somewhat controversial. A genetic test identifying a mutation in one of the genes involved with this condition 2.
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